In a new study from Sanford-Burnham Medical Research Institute , researchers have used human pluripotent stem cells to generate new hair. The study represents the first step toward the development of a cell-based treatment for people with hair loss. In the United States alone, more than 40 million men and 21 million women are affected1 by hair loss. The research was published online in PLOS One yesterday. We have developed a method using human pluripotent stem cells to create new cells capable of initiating2 human hair growth. The method is a marked improvement over current methods that rely on transplanting existing hair follicles from one part of the head to another, said Alexey Terskikh, Ph.D., associate professor in the Development, Aging, and Regeneration Program at Sanford-Burnham. Our stem cell method provides an unlimited3 source of cells from the patient for transplantation and isnt limited by the availability of existing hair follicles.The research team developed a protocol4 that coaxed5 human pluripotent stem cells to become dermal6 papilla cells. They are a unique population of cells that regulate hair-follicle formation and growth cycle. Human dermal papilla cells on their own are not suitable for hair transplants because they cannot be obtained in necessary amounts and rapidly lose their ability to induce hair-follicle formation in culture.In adults, dermal papilla cells cannot be readily amplified7 outside of the body and they quickly lose their hair-inducing properties, said Terskikh. We developed a protocol to drive human pluripotent stem cells to differentiate8 into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice.Our next step is to transplant human dermal papilla cells derived9 from human pluripotent stem cells back into human subjects, said Terskikh. We are currently seeking partnerships10 to implement11 this final step.
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1 affected adj.不自然的，假装的 参考例句： She showed an affected interest in our subject.她假装对大家的课题感到兴趣。 His manners are affected.他的态度不自然。
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